AMD, based in Santa Clara, California, designs the Instinct MI series of data centre GPUs and Helios rack-scale systems. In October 2025 it signed a multi-year deal to supply OpenAI with Instinct GPUs, giving OpenAI an option to take up to a 10% stake, and it also has an agreement with Anthropic for up to 2 gigawatts of MI450 GPUs.
At a glance
| Price from | Custom |
| Best for | Cloud providers and AI labs that want a second GPU supplier |
From AMD's own website.
What stands out
- Large memory on Instinct GPUs
- Major supply deals with OpenAI and Anthropic
Worth knowing
- Software stack less mature than CUDA
- Much smaller AI share than Nvidia
How it ranks
AMD is ranked 2nd of 10 in Best AI Chip Companies (Lister Score 95.9).
#2 in Best AI Chip Companies · Lister Score 95.9
AMD's data centre segment, which includes its EPYC CPUs, earned $6.7 billion in the second quarter of 2026, up 107% year on year..
| Rank | Best AI Chip Companies | Score |
|---|---|---|
| 1 | Nvidia | 97.4 |
| 2 | AMD | 95.9 |
| 3 | Google (TPU) | 94.7 |
| 4 | Broadcom | 93.5 |
| 5 | Amazon Web Services (Trainium) | 92.2 |
| 6 | Huawei (Ascend) | 90.8 |
| 7 | Cerebras | 89.5 |
| 8 | Intel | 88.1 |
| 9 | Qualcomm | 86.6 |
| 10 | Tenstorrent | 85.2 |
Frequently asked questions
How does AMD rank on Lister?
AMD is ranked 2nd of 10 in Best AI Chip Companies (Lister Score 95.9).
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