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SOFTWARE/SECURITY/DATA LOSS PREVENTION/DATA LOSS PREVENTION SOFTWARE FOR MICROSOFT 365

Best Data loss prevention software for Microsoft 365

10 software tools ranked, each with a short verdict.

VERIFIEDLISTER SCORE · UPDATED

Best Data loss prevention software for Microsoft 365: Top 10 Ranked. Guardz ranks first, with a Lister Score of 98.0.

Guardz comes first on this list for Managed Service Providers, and connects identity, endpoint, email, and data in one connected platform. miniOrange is built for IT security teams managing complex identities, and offers one-click secure access to cloud and legacy applications via SSO. Nudge Security delivers full visibility on Day One without lengthy integration work.
Best Data loss prevention software for Microsoft 365, compared
RANKENTRYBEST FORSCOREFROM
1GuardzGuardz is a unified cybersecurity platform designed for managed service providersManaged Service Providers98.0–
2miniOrangeProtects endpoints with desktop MFA and user lifecycle managementIT security teams managing complex identities94.0–
3Nudge SecurityAutomatically guides users toward secure decisions at scaleSecurity teams94.0–
4CyeraUses AI-native classification that learns the business to deliver high precisionSecurity teams managing complex cloud environments90.0–
5KnowBe4Delivers timely education with realistic phishing simulations–88.0–
6StracProvides over fifty-five native integrations across SaaS, cloud, browser, endpoint and AI surfacesSecurity, IT and compliance teams88.0–
7VirtruIntegrates with existing workflows for email and filesEmail and Google Workspace security88.0$9 / user / month
8SyncDogOffers full separation of corporate and personal data–86.0–
9Nightfall AIDeploys without a tuning cycle using pre-trained detectionSecurity teams managing AI and employee data84.0–
10Proofpoint Email SecurityStops all human and agent-targeted attacks across channelsMid-market to enterprise organisations requiring email security and governance82.0Custom
CURATED · UPDATED HOW WE RANK →

How to choose

Start from what you need it for. Where each entry fits best:

  • Guardz (#1): Managed Service Providers
  • miniOrange (#2): IT security teams managing complex identities
  • Nudge Security (#3): Security teams
  • Cyera (#4): Security teams managing complex cloud environments
  • Strac (#6): Security, IT and compliance teams
  • Virtru (#7): Email and Google Workspace security
  • Nightfall AI (#9): Security teams managing AI and employee data
  • Proofpoint Email Security (#10): Mid-market to enterprise organisations requiring email security and governance

Each entry's Lister Score on this ranking weighs fit to the list (40%), evidence on the site (20%), published detail (20%) and buying signals (20%).

Each entry's full verdict is below.

The ranking, in detail

01

Guardz

Unified workspace security platform built for MSPs

Guardz is a unified cybersecurity platform designed for managed service providers. It combines detection, response, and security controls into one AI-native system.

Best for: Managed Service Providers
PROS
  • The product provides 24/7 AI-native detection and response capabilities.
  • Guardz connects identity, endpoint, email, and data in one connected platform.
98.0
02

miniOrange

Complete IAM, PAM, UEM, and Data Privacy solutions

miniOrange provides a comprehensive suite of identity and access management solutions. It covers workforce IAM, customer identity, privileged access, and endpoint security.

Best for: IT security teams managing complex identities
PROS
  • The product offers one-click secure access to cloud and legacy applications via SSO.
  • The product protects endpoints with desktop MFA and user lifecycle management.
94.0
03

Nudge Security

Secure your fastest-growing attack surface

Nudge Security is a SaaS and AI security platform that secures the workforce edge. It provides SSPM, shadow IT discovery, and governance capabilities.

Best for: Security teams
PROS
  • The product delivers full visibility on Day One without lengthy integration work.
  • Nudge Security automatically guides users toward secure decisions at scale.
94.0
04

Cyera

The unified AI security platform for data protection

Cyera is an AI security platform designed to secure data and artificial intelligence systems. It enables organisations to reduce data risk in real time while strengthening compliance.

Best for: Security teams managing complex cloud environments
PROS
  • The product deploys in minutes across any environment with an agentless design.
  • The product uses AI-native classification that learns the business to deliver high precision.
90.0
05

KnowBe4

Secure your Digital Workforce: Human + AI

KnowBe4 thwarts threats by weaving risk deterrence into everyone's workday through training and security tools.

PROS
  • The product delivers personalised security education reinforced by realistic phishing simulations.
  • The product provides layered cloud defences that block threats without requiring manual tuning.
88.0
06

Strac

AI-native data security for SaaS, cloud, endpoints & AI agents

Strac is an AI-native data security platform. It discovers, classifies and remediates sensitive data across SaaS apps, cloud, browsers, endpoints and AI tools.

Best for: Security, IT and compliance teams
PROS
  • The product offers built-in remediation capabilities such as redaction, masking, blocking, labelling, revoking access or notifying in real time.
  • Strac provides over fifty-five native integrations across SaaS, cloud, browser, endpoint and AI surfaces.
88.0
07

Virtru

Virtru is a data security platform that enables secure information sharing without sacrificing control. It utilises the Trusted Data Format to bind granular policy and access controls to sensitive data.

Best for: Email and Google Workspace security
PROS
  • Easy to install and use
  • Great Gmail and Outlook integration
CONS
  • Limited document rights management compared to enterprise suites
88.0
08

SyncDog

Mobile data security done right

SyncDog secures work data on personal devices by separating corporate and personal information. This approach provides a secure environment without compromising user privacy.

PROS
  • The product uses FIPS 140-2 certified AES 256-bit encryption.
  • SyncDog offers full separation of corporate and personal data.
86.0
09

Nightfall AI

AI moves your data. Nightfall controls it.

Nightfall AI is an AI security platform that controls data movement across agents and people. It prevents exposure and responds with context.

Best for: Security teams managing AI and employee data
PROS
  • The product deploys without a tuning cycle using pre-trained detection.
  • The product offers ninety-five percent detection precision and live deployment in one hour.
84.0
10

Proofpoint Email Security

Cloud-based email protection with signature and archive management

Proofpoint Email Security provides industry-leading threat protection via API or gateway.

Best for: Mid-market to enterprise organisations requiring email security and governance
PROS
  • Robust threat detection with integrated email governance and compliance tools
  • Comprehensive audit trails and reporting for regulatory requirements
CONS
  • Complex feature set may overwhelm organisations with basic needs
  • Higher implementation costs and longer deployment timelines
82.0

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Frequently asked questions

What is the best Data loss prevention software for Microsoft 365?

Guardz ranks first on Lister. Guardz is a unified cybersecurity platform designed for managed service providers. It combines detection, response, and security controls into one AI-native system.

What are the top 10 Data loss prevention software for Microsoft 365?

1. Guardz; 2. miniOrange; 3. Nudge Security; 4. Cyera; 5. KnowBe4; 6. Strac; 7. Virtru; 8. SyncDog; 9. Nightfall AI; 10. Proofpoint Email Security.

Are there free options for Data loss prevention software for Microsoft 365?

No free option is confirmed in the recorded pricing for this ranking. Check each provider's pricing page for current plans and trials.

What do the top four say they are built for?

Guardz says it is built for Managed Service Providers, and miniOrange for IT security teams managing complex identities. Nudge Security says it is built for Security teams, and Cyera for Security teams managing complex cloud environments.

Sources

Where we checked each company's facts, and when.

Sources for 5 more companies

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