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BigHat Biosciences

AI-designed antibody therapies

Ranked #8 in Best AI Drug Discovery Startups.

BigHat Biosciences, founded in 2019 in San Mateo, California, uses its Milliner platform, which combines AI with a high-speed lab, to design antibody drugs. It raised a $75 million Series C co-led by DFJ Growth and Premji Invest in September 2026, bringing total funding to $223 million.

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At a glance

Price fromCustom
Best forPartners in oncology and antibody therapeutics

From BigHat Biosciences's own website.

What stands out

  • Lead program now in Phase 1
  • Backed by Amgen, Eli Lilly and Merck's fund

Worth knowing

  • Early clinical stage
  • Smaller funding than the leaders

How it ranks

BigHat Biosciences is ranked 8th of 10 in Best AI Drug Discovery Startups (Lister Score 88.1).

#8 in Best AI Drug Discovery Startups · Lister Score 88.1

BigHat dosed the first patient in a Phase 1 study of BHB810, an antibody-drug conjugate for gastrointestinal cancers, in September 2026..

RankBest AI Drug Discovery StartupsScore
1Isomorphic Labs97.1
2Xaira Therapeutics95.8
3Chai Discovery94.6
4Enveda93.3
5insitro92.0
6Formation Bio90.7
7Genesis Molecular AI89.4
8BigHat Biosciences88.1
9Terray Therapeutics86.7
10Cradle85.3

Frequently asked questions

How does BigHat Biosciences rank on Lister?

BigHat Biosciences is ranked 8th of 10 in Best AI Drug Discovery Startups (Lister Score 88.1).

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#8 in Best AI Drug Discovery Startups
RANKED #8 ON LISTERBest AI Drug Discovery Startups