Key takeaways
- Top pick: Aidoc, best for: healthcare organisations seeking scalable AI integration. In January 2026 the FDA cleared Aidoc's CARE foundation model for 11 new acute triage indications, which Aidoc says is the first double-digit clearance from a single AI model.
- Also near the top: Exo, best for: Clinicians who want point-of-care ultrasound at the bedside; and Eko Health, best for: Primary care clinicians screening for heart disease.
- How it was ranked: 10 startups compared. Each verdict is below.
Best Medical Device Startups Using AI: Top 10 Ranked. Aidoc ranks first, with a Lister Score of 96.9.
Aidoc leads AI medical device startups globally, with an FDA-cleared foundation model for radiology triage and more than $500 million raised, and
Exo is the most advanced in AI-guided handheld ultrasound.
Eko Health is the pick for AI stethoscopes,
Viz.ai for stroke alerts in hospitals, and
Prenuvo for AI-supported whole-body MRI screening.
Best Medical Device Startups Using AI in 2026, compared| RANK | ENTRY | BEST FOR | SCORE | FROM |
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| 1 |  AidocIn January 2026 the FDA cleared Aidoc's CARE foundation model for 11 new acute triage indications, which Aidoc says is the first double-digit clearance from a single AI model. | healthcare organisations seeking scalable AI integration | 96.9 | – |
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| 2 |  ExoExo Iris carries 14 FDA-cleared AI algorithms, according to Exo. | Clinicians who want point-of-care ultrasound at the bedside | 95.6 | Not public |
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| 3 |  Eko HealthEko says it holds 9 FDA clearances and has sold more than 700,000 stethoscopes. | Primary care clinicians screening for heart disease | 94.3 | $449 |
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| 4 |  Viz.aiViz.ai marked 10 years of operations in July 2026 and says its platform is used in 2,000 hospitals. | healthcare providers seeking automated disease detection | 93.1 | – |
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| 5 |  CleerlyAI coronary plaque analysis received a Category I CPT code effective January 2026, following coverage by several Medicare administrative contractors. | Cardiology practices assessing coronary artery disease | 91.8 | Custom |
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| 6 |  PrenuvoPrenuvo says it has passed 110,000 members. | People who want proactive full-body screening | 90.5 | From $1,199 |
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| 7 |  UltromicsAn American Heart Association AI Assessment Lab report found that EchoGo Heart Failure may identify HFpEF earlier than standard care. | – | 89.2 | – |
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| 8 |  Qure.aiQure.ai raised a $65 million Series D in September 2024. | clinicians requiring rapid diagnostic support | 87.9 | – |
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| 9 |  AnumanaAnumana received FDA clearance for its pulmonary hypertension algorithm in March 2026 and its cardiac amyloidosis algorithm in April 2026. | Health systems screening for hidden heart disease | 86.6 | Custom |
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| 10 |  ProprioProprio received its fourth FDA clearance for Paradigm, for the Picasso registration feature, in January 2026. | Spine surgeons who want navigation without extra imaging | 85.3 | Custom |
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How to choose
Start from what you need it for. Where each entry fits best:
- Aidoc (#1): healthcare organisations seeking scalable AI integration
- Exo (#2): Clinicians who want point-of-care ultrasound at the bedside
- Eko Health (#3): Primary care clinicians screening for heart disease
- Viz.ai (#4): healthcare providers seeking automated disease detection
- Cleerly (#5): Cardiology practices assessing coronary artery disease
- Prenuvo (#6): People who want proactive full-body screening
- Qure.ai (#8): clinicians requiring rapid diagnostic support
- Anumana (#9): Health systems screening for hidden heart disease
- Proprio (#10): Spine surgeons who want navigation without extra imaging
Each entry's full verdict is below.
The ranking, in detail
01
Always on healthcare AI connecting all points of care
Aidoc, founded in 2016 in Tel Aviv, makes clinical AI that flags urgent findings on medical images and routes them to care teams. It raised a $150 million Series E led by Growth Equity at Goldman Sachs Alternatives, taking total funding above $500 million.
PROS- The AI tool integrates seamlessly with existing IT infrastructure like PACS and EHR systems.
- Aidoc offers continuous performance monitoring and rapid scalability for health networks.
CONS- The platform currently supports English only for certain features.
- Best for
- healthcare organisations seeking scalable AI integration
- Where it falls short
- It supports English only for certain features.
- Pick something else if
- you need multilingual support.
96.9
02
AI-guided handheld ultrasound
Exo, founded in 2015 and based in Santa Clara, California, makes Exo Iris, a handheld ultrasound probe that works with a phone app and AI tools that help clinicians capture and read images. Exo Iris received FDA 510(k) clearance in August 2021, and two AI lung applications were cleared in June 2025.
PROS- Many FDA-cleared AI tools
- Pocket-sized device
CONS- Crowded handheld ultrasound market
- Price not published
- Best for
- Clinicians who want point-of-care ultrasound at the bedside
- Where it falls short
- The price is not published, so you cannot determine costs upfront.
- Pick something else if
- you need to know the exact cost before committing.
95.6
03
AI-supported digital stethoscopes
Eko Health, founded in 2013 and based in Emeryville, California, makes digital stethoscopes and AI software that help clinicians detect heart and lung disease, including the CORE 500, which combines a 3-lead ECG with AI-supported arrhythmia detection. It raised a $41 million Series D in June 2024.
PROS- On open sale at a low price
- Multiple FDA clearances
CONS- Some features tied to a paid membership
- Funding totals vary by source
- Best for
- Primary care clinicians screening for heart disease
- Where it falls short
- Some features are tied to a paid membership.
- Pick something else if
- you need all features without extra costs.
94.3
04
The proven AI-powered care coordination platform for healthcare providers.
Viz.ai, founded in 2016 and based in San Francisco, makes FDA-cleared AI that detects suspected strokes and other conditions on scans and alerts care teams on their phones. It raised a $100 million Series D in 2022.
PROS- Viz.ai autodetects suspected diseases across multiple therapeutic areas within seconds.
- The AI tool connects clinical teams instantly upon detecting a suspected disease.
- Best for
- healthcare providers seeking automated disease detection
93.1
05
AI analysis of heart CT scans
Cleerly makes FDA-cleared AI that analyses coronary CT scans for plaque and narrowing to assess a patient's risk of heart disease. It raised an additional $106 million, led by Insight Partners with Battery Ventures, as an extension of its Series C.
PROS- Growing insurance coverage
- FDA cleared
CONS- Depends on CT imaging capacity
- Price not published
- Best for
- Cardiology practices assessing coronary artery disease
- Where it falls short
- It does not publish its price, so you cannot determine the cost before contacting the company.
- Pick something else if
- you need to know the exact cost upfront.
91.8
06
Whole-body MRI with AI-supported reports
Prenuvo runs clinics offering whole-body MRI screening and has FDA clearance for an AI-powered body composition report covering fat, muscle and organ volumes. It raised a $120 million Series B co-led by Forerunner Ventures, Left Lane Capital and Felicis.
PROS- Published prices
- FDA-cleared AI reporting
CONS- Paid out of pocket
- Clinics in selected cities only
- Best for
- People who want proactive full-body screening
- Where it falls short
- Paid out of pocket.
- Pick something else if
- you need coverage by insurance or live outside its clinic locations.
90.5
07
Advanced AI for heart failure detection
Ultromics, a spinout from the University of Oxford, makes EchoGo, AI software that reads standard echocardiograms to detect heart failure, including hard-to-diagnose HFpEF, without new hardware. It raised a $55 million Series C co-led by L&G, Allegis Capital and Lightrock in July 2025.
PROS- The AI tool is FDA 510(k) cleared and holds Breakthrough device Designation.
- Ultromics integrates seamlessly with existing ultrasound and PACS environments without workflow changes.
- Best for
- Hospitals using standard echo workflows
89.2
08
AI assistance for accelerated healthcare
Qure.ai, founded in 2016 and based in Mumbai, makes AI that reads chest X-rays, CT scans and other medical images to flag conditions such as tuberculosis, lung nodules and brain bleeds.
PROS- The AI tool processes chest X-rays in just twenty seconds with comprehensive findings.
- The AI tool can be deployed on cloud or on-premise systems and is clinically validated.
- Best for
- clinicians requiring rapid diagnostic support
- Where it falls short
- It focuses on chest X-rays and does not mention other imaging modalities.
- Pick something else if
- you need support for imaging types beyond chest X-rays.
87.9
09
AI that finds heart disease in a standard ECG
Anumana makes ECG-AI algorithms that detect heart conditions, including low ejection fraction, pulmonary hypertension and cardiac amyloidosis, from a standard 12-lead ECG.
PROS- Three FDA-cleared algorithms
- Uses a test hospitals already run
CONS- Funding not widely disclosed
- Early commercial stage
- Best for
- Health systems screening for hidden heart disease
- Where it falls short
- It is in an early commercial stage with funding not widely disclosed.
- Pick something else if
- you need a mature vendor with transparent financial backing.
86.6
10
AI surgical guidance without radiation
Proprio, based in Seattle, makes Paradigm, a surgical navigation platform that uses light field imaging, computer vision and machine learning to build a continuous, radiation-free 3D view of the patient during spine surgery. It raised a $43 million Series B in 2023.
PROS- Four FDA clearances
- Radiation-free 3D view
CONS- Spine surgery focus
- Smaller funding than peers
- Best for
- Spine surgeons who want navigation without extra imaging
- Where it falls short
- It focuses exclusively on spine surgery.
- Pick something else if
- you need solutions for other surgical specialties.
85.3
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Frequently asked questions
What is the best Medical Device Startups Using AI?
Aidoc ranks first on Lister. Aidoc, founded in 2016 in Tel Aviv, makes clinical AI that flags urgent findings on medical images and routes them to care teams. It raised a $150 million Series E led by Growth Equity at Goldman Sachs Alternatives, taking total funding above $500 million.
What are the top 10 Medical Device Startups Using AI?
1. Aidoc; 2. Exo; 3. Eko Health; 4. Viz.ai; 5. Cleerly; 6. Prenuvo; 7. Ultromics; 8. Qure.ai; 9. Anumana; 10. Proprio.
Sources
Where we checked each company's facts, and when.
Some links on Lister are affiliate links. Rankings are not affected.
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