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Proprio

AI surgical guidance without radiation

Ranked #10 in Best Medical Device Startups Using AI.

Proprio, based in Seattle, makes Paradigm, a surgical navigation platform that uses light field imaging, computer vision and machine learning to build a continuous, radiation-free 3D view of the patient during spine surgery. It raised a $43 million Series B in 2023.

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At a glance

Price fromCustom
Best forSpine surgeons who want navigation without extra imaging

From Proprio's own website.

What stands out

  • Four FDA clearances
  • Radiation-free 3D view

Worth knowing

  • Spine surgery focus
  • Smaller funding than peers

How it ranks

Proprio is ranked 10th of 10 in Best Medical Device Startups Using AI (Lister Score 85.3).

#10 in Best Medical Device Startups Using AI · Lister Score 85.3

Proprio received its fourth FDA clearance for Paradigm, for the Picasso registration feature, in January 2026..

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6Prenuvo90.5
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8Qure.ai87.9
9Anumana86.6
10Proprio85.3

Frequently asked questions

How does Proprio rank on Lister?

Proprio is ranked 10th of 10 in Best Medical Device Startups Using AI (Lister Score 85.3).

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#10 in Best Medical Device Startups Using AI
RANKED #10 ON LISTERBest Medical Device Startups Using AI