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Life Biosciences

Partial epigenetic reprogramming therapies

Ranked #6 in Best Longevity Startups.

Life Biosciences, based in Boston, develops cellular rejuvenation therapies using partial epigenetic reprogramming, led by ER-100 for optic neuropathies. It announced an $80 million Series D in April 2026 and dosed the first patient in its ER-100 trial in June 2026.

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At a glance

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Best forPartners in eye disease and reprogramming

From Life Biosciences's own website.

What stands out

  • First reprogramming therapy in humans
  • Clear initial indication

Worth knowing

  • Phase 1 stage
  • Narrow first target in eye disease

How it ranks

Life Biosciences is ranked 6th of 10 in Best Longevity Startups (Lister Score 90.4).

#6 in Best Longevity Startups · Lister Score 90.4

The FDA cleared Life Biosciences' IND for ER-100 in January 2026, which the company calls the first partial epigenetic reprogramming therapy to reach human trials..

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Frequently asked questions

How does Life Biosciences rank on Lister?

Life Biosciences is ranked 6th of 10 in Best Longevity Startups (Lister Score 90.4).

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#6 in Best Longevity Startups
RANKED #6 ON LISTERBest Longevity Startups