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Loyal

Lifespan drugs for dogs

Ranked #4 in Best Longevity Startups.

Loyal, based in San Francisco, develops drugs intended to extend the healthy lifespan of dogs, led by LOY-002 for senior dogs. It raised a $100 million Series C led by age1 in February 2026, taking total funding past $250 million.

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At a glance

Price fromNot public
Best forVets and owners of senior and large dogs

From Loyal's own website.

What stands out

  • Furthest along the regulatory path
  • Shorter dog lifespans allow faster proof

Worth knowing

  • Not yet approved for sale
  • Animal health only

How it ranks

Loyal is ranked 4th of 10 in Best Longevity Startups (Lister Score 93.1).

#4 in Best Longevity Startups · Lister Score 93.1

In January 2026 the FDA accepted the target animal safety section of LOY-002's conditional approval application, the second of three major parts..

RankBest Longevity StartupsScore
1Altos Labs96.8
2NewLimit95.6
3Retro Biosciences94.3
4Loyal93.1
5Function Health91.8
6Life Biosciences90.4
7Juvenescence89.1
8Rubedo Life Sciences87.7
9Cambrian Bio86.4
10Gameto85.0

Frequently asked questions

How does Loyal rank on Lister?

Loyal is ranked 4th of 10 in Best Longevity Startups (Lister Score 93.1).

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#4 in Best Longevity Startups
RANKED #4 ON LISTERBest Longevity Startups